Septicemia is a life-threatening condition that may cause multiple organ failure. Because of the FDA alert and the dangers of Invokana, U.S. product liability lawyers are coordinating to pursue … This Boxed Warning also applies to Invokamet and Invokamet XR, combination products that contain canagliflozin and metformin. Invokana prevents the kidneys from reabsorbing glucose. The Dangers Of Invokana. Some of these side effects can be life threatening. Other dangers with Invokana include: acute kidney risk and genital infections. Invokana Concerning Lawsuits. Invokana (canagliflozin) is a prescription drug used with diet and exercise to lower blood sugar in adults with type 2 diabetes. According to the manufacturer, when Invokana is used as part of a healthy lifestyle (diet and exercise), patients with Type 2 diabetes may enjoy weight loss, lowered blood pressure, and more regulated blood sugar levels. Janssen Pharmaceuticals is a subsidiary of Johnson & Johnson that manufactures Invokana. Invokana dangers were seen early on by researchers. These serious health risks have prompted hundreds of injured victims and their families to file product liability lawsuits against Johnson & Johnson. If true, their negligence makes them liable to compensate those who were harmed by the drug. Be sure to tell your doctor if you fall into any of these categories. Our experienced dangerous drug attorneys have helped many victims of dangerous drugs recover compensation for damages. A case manager will inform you of your legal options and the next steps to take. However, the number of serious side effects linked to Invokana over the last several years is alarming, to say the least. Many Invokana® lawsuits involve cases of diabetic ketoacidosis reported by doctors and patients. Injuries claimed by plaintiffs in these lawsuits include hospitalizations, surgery, extensive medical treatments, amputation, permanent disability, and even death. The additional Invokana dangers led to an Invokana FDA black box warning, the strictest and most severe warning given to medications in the public market. Let us schedule a free consultation to discuss your legal rights. In addition, bone fractures seem to occur in patients taking Invokana. Invokana is one of many potentially dangerous drugs used to treat type 2 diabetes, others include: Available for Android and iOS devices. Urinary tract infections and frequent urination are other common reactions. This might also increase your risk for a fall. You could be at risk of dehydration if you: Low blood pressure (hypotension) may occur with Invokana treatment. Les médecins prescrivent Invokana en plus de l'alimentation et de l'exercice. Dangers of Invokana The Food and Drug Administration ( FDA ) issued a safety communication on May 15, 2015 regarding the serious conditions that are associated with Invokana and other SGLT2 inhibitors. While all of these minerals are essential to the proper function of the body, they can cause problems when levels become too high. Are You Suffering Symptoms From Invokana. Tell your doctor all medications you use. Seek medical attention immediately if you have fever or if you are feeling very weak, tired or uncomfortable and you have these symptoms in the area between and around your anus and genitals: Invokana is also associated with some drug interactions. Is Invokana Safe . Speak with one of our medical malpractice attorneys to find out more about Invokana lawsuits and how to protect your legal rights. An Invokana leg amputation lawsuit was filed by a woman who lost her right leg allegedly due to the side effects of Invokana. high potassium levels in your blood, which can affect your heart and may be serious, phenytoin or phenobarbital (for seizures), if you have a serious allergy to canagliflozin or any ingredient in Invokana, if you have severe kidney impairment or are on dialysis. These medications are designed to treat type 2 diabetes. Invokana is an important medication that is approved by the Food and Drug Administration (FDA) for the treatment of type 2 diabetes and to reduce the occurrence of stroke, heart attack, and cardiovascular disease in adults with type 2 diabetes. There are several potential symptoms that could be the result of a much more serious Invokana-related problem including: Chest pains. you take certain medicines for blood pressure, such as diuretics (water pills), ACE inhibitors, or Angiotensin receptor blockers. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Invokana is used in combination with diet and exercise and works to control blood sugar levels by blocking a natural enzyme in the body, therefore stopping some kidney functions and increasing the amount of sugar removed in the urine. Plaintiffs further claim that had they known about the risks, they would have opted for a different method of treatment. Studies conducted around the time of the FDA warning indicated that the risk of amputation for patients taking Invokana was 5.9 out of every 1,000 patients, as compared to just 2.8 out of every 1,000 patients taking a placebo. However, patients who took the drug have reported many other side effects that were not properly listed by the drug company when the product was made available to the public. SGLT2 inhibitors lower blood sugar by blocking a certain protein and causing the kidneys to remove sugar from the body through the urine. Other names for the drug include Invokamet and Invokamet XR. To find out more, contact Brown, Christie & Green by filling out our online form. Dehydration may make you feel dizzy, lightheaded faint, or weak, especially when you stand up (orthostatic hypotension). Recently, the medication has been under heavy scrutiny for being linked to serious and life-threatening complications in some patients. Call us at 877-721-4451 or use the contact form with a summary of your situation. Since the FDA warning, more attention has been paid to the dangers of Invokana – by patients and the medical and legal communities. If you take the 300 mg dose of Invokana, are 75 years of age or older, or take a loop diuretic (such as furosemide), you may be at greater risk of dehydration. Therefore, hundreds of thousands of people who take Invokana are completely unaware that a seemingly innocent cut on a toe, may lead to amputation because of their Invokana use. Patients received INVOKANA 100 mg (N=833), INVOKANA 300 mg (N=834) or placebo (N=646) once daily. 2011, 2012. Be sure to tell your doctor and pharmacist about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Invokana may interact with rifampin or digoxin. Speak to your doctor if you think you fall into these categories. Invokana Side Effects . While using Invokana, the kidneys remove sugar from the body. Unfortunately, this drug comes with risks, and some people suffer serious side effects without warning. If you have any of these symptoms and your blood sugar is consistently higher than 300 milligrams per deciliter, you should seek emergency treatment. These serious health risks have prompted hundreds of injured victims and their families to file product liability lawsuits against Johnson & Johnson. The total number of amputations were 162 for Invokana and 33 for the placebo group. FDA reviewers were divided over the safety and effectiveness of Invokana before approving it for the market in 2013. This allows excess glucose (sugar) to be expelled through the urine. There are other serious side effects with Invokana that you should discuss with your doctor. Ketoacidosis can happen with Invokana even if your blood sugar is less than 250 mg/dL. Invokana is a medication commonly used to treat Type 2 diabetes, but unfortunately, has been linked to several risks including diabetic ketoacidosis. If you get any of the following symptoms, tell your doctor immediately: Sudden (acute) kidney injury is a possible serious side effect with Invokana. Accessed May 26, 2020 at, FDA Drug Safety Communication: FDA confirms increased risk of leg and foot amputations with the diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR). In May 2015, the FDA warned about the danger of diabetic ketoacidosis. If you believe that you have been the victim of medical negligence, contact Brown, Christie & Green today for a free case evaluation. Her complaint cites Janssen’s dangerous off-label promotion of the drug for treatment of hypertension. This field is for validation purposes and should be left unchanged. Last updated on May 25, 2020. Several lawsuits have been filed by patients claiming that the manufacturers of Invokana failed to properly warn doctors and patients about the risks. Is Invokana Bad For You . Unlike other diabetes medications that are designed to help the body produce more insulin to metabolize sugar, Invokana actually forces the body to filter sugar out of the blood by … At that time, the agency acted against the advice of prominent physicians and researchers in approving the drug for the treatment of Type-2 Diabetes. What are the dangers of Invokana? More than 1,000 lawsuits have been filed against drug makers Janssen Pharmaceuticals and Johnson & Johnson, which Janssen is a division of. Especially tell your doctor and pharmacist if you take: Tell your doctor if you are pregnant or plan to become pregnant while taking Invokana. Invokana (also called canagliflozin) is a subtype 2 sodium-glucose transport inhibitor (SGLT2 inhibitor) that is used to treat this common condition. Accessed May 25, 2020 at, FDA warns about rare occurrences of a serious infection of the genital area with SGLT2 inhibitors for diabetes. Fournier’s Gangrene, otherwise known as necrotizing fasciitis, is a flesh-eating rash that infects the area between the rectum and genitals. Here is what you need to know to help you decide: worth it or not? The Dangers of Invokana and SGLT2 Inhibitors. Currently, Invokana is the only drug classified as an SLGT-2 inhibitor that carries the significant risk of amputation. One of the dangers of Invokana is an infection known as Fournier’s Gangrene. It can require hospitalization, multiple surgeries, and may lead to death. Invokana used alone doesn’t lower blood sugars (measured by the A1C blood test) enough to make it effective as a single agent for diabetes. Two clinical studies (CANVAS, CANVAS-R trial) in patients with type 2 diabetes and heart disease (or at risk for heart disease) showed that amputations occurred about twice as often in those patients taking Invokana as in patients treated with an inactive placebo. Invokana Side Effects And Dangers Doctors have a responsibility to inform you of the dangers and side effects, but sometimes they fail to adequately address all the possible concerns. Invokana and Farxiga lawsuits account for most of the SGLT2 inhibitor diabetes drug cases filed in federal court. Some of the top warnings associated with Invokana (canagliflozin) treatment include the risk of amputation of a lower limb, dehydration and low blood pressure, genital yeast infections in men and women, serious allergic reactions and kidney problems. Invokana causes increased urination, which may put you at risk of dehydration (the loss of too much body water). Left untreated or unmanaged, type 2 diabetes can eventually lead to nerve damage, blindness, heart disease, kidney failure, high blood pressure, and other serious problems. The risk is significant, and in 2015, the U.S. Food and Drug Administration (FDA) issued a “boxed warning”. Signs and symptoms of low blood sugar may include: Fournier’s Gangrene is a rare but serious bacterial infection that causes damage to the tissue under your skin (necrotizing fasciitis) in the area between and around the anus and genitals (perineum). 3.8% (with the 300 mg dose) and 0.7% (inactive placebo). Accessed May 25, 2020 at. The medicine can also put you in danger of lower-limb amputation and severe … This risk is heightened for patients with a history of: Patients taking Invokana who have these or other conditions may be at a much higher risk of amputation, and should be careful to monitor their overall health. However, they can cause urinary tract infections and diabetic ketoacidosis. Also discuss the best way to feed your baby if you are taking Invokana. The potentially dangerous side effects of SGLT2 Inhibitors have caused many people to file lawsuits. Janssen sponsors medical studies and conducts clinical trials hoping to expand Invokana’s FDA-approved uses. The severe side … Oral prescription or over-the-counter topical antifungal treatment may be treatment options. The three most common side effects for Invokana, as listed on the product’s website, are genital yeast infections, changes in urination and urinary tract infections. Andrew Holcomb was selected as a 'Top Lawyer' by the Houstonia Magazine. The FDA has recently issued a public statement warning consumers of the potential dangers of using Invokana and other drugs that are members of the SGLT2 inhibitors class of medications. This drug is manufactured by Janssen Pharmaceuticals, which is a division of Johnson & Johnson. Invokana. Many people take Invokana to manage diabetes and Crestor to reduce their cholesterol levels. Ketones are produced by your body when there is not enough insulin to effectively break down glucose. Brown, Christie & Green achieved the 'Largest Nursing Home Abuse Verdict' in Texas for 2011 on behalf of their clients according to VerdictSearch's records. Invokana was developed by Janssen, an offshoot of Johnson & Johnson. Tell your doctor if you have any signs or symptoms of a urinary tract infection such as: burning feeling while urinating, need to urinate often or right away, pain in the lower part of your stomach (pelvis), or blood in the urine. Invokana and Invokament In the United States, diabetes is seventh on the list of causes of death. Invokana is the best-selling inhibitor drug on the market for Type 2 diabetes. Your doctor may need to temporarily discontinue your treatment. En savoir plus sur les effets secondaires, les avertissements, la posologie, et plus encore. Diabetics must pay close attention to their sugar levels, meal … Some of the most serious risks that are currently associated with Invokana include: Bone fractures. Before you start treatment with Invokana, tell your doctor if you have a history of urinary tract infections or problems with urination. Another one of the known dangers of Invokana is an increased risk of lower limb amputations. Learn about side effects, dosage, alternatives, and more. People can also suffer from serious allergic reactions from Invokana as well. Urinary Tract Infection 3. According to the Institute […] If you have been diagnosed with Type 2 diabetes and your doctor has recommended you start Invokana, you may find it helpful to learn more about the dangers of Invokana, and explore your legal rights. They refuse to give up. Janssen Pharmaceutical Companies. The most common symptoms of diabetic ketoacidosis include: Any of these symptoms – or a combination thereof – should be taken seriously, and you should contact your doctor right away. Invokana Class Action Lawsuit . Compensation for Invokana Injuries. Invokana Information for Healthcare Professionals. Invokana can cause potentially dangerous problems in some people. Severe Invokana side effects include: Dehydration; Diabetic ketoacidosis; Kidney damage; Hypoglycemia (low blood sugar) Fournier's gangrene; Bone fractures; Amputation of lower limbs Amputations of the toe and middle of the foot were the most common; however, amputations involving the leg, either below or above the knee, also occurred. Symptoms of a vaginal yeast infection in women (also called vulvovaginitis or candidiasis): In Invokana studies, the overall incidence of genital yeast infections in women was 10.6% (with the 100 mg dose), 11.6% (with the 300 mg dose) and 2.8% (inactive placebo). Recently touted as the latest greatest drug for those suffering from Type 2 Diabetes, Invokana and similar SGLT2 inhibitors aren’t without serious side effects. Type 2 Diabetes is a fact of life for a large number of people throughout the country. Yeast Infection Of Vagina And Vulva What are the Dangers of Invokana? Initially hailed as a “miracle drug” for the treatment of type-2 diabetes, Invokana and other drugs of the gliflozin class have been linked to numerous serious side effects. Diabetes occurs when the body does not produce or use insulin correctly. This can happen in both women and men. Just this past Friday the Food and Drug Adminstration ( FDA) said that SGLT2 (sodium-glucose contransporter-2) inhibitors, including Empaglifliozin (Jardiance), Dapagliflozin (Farxiga), and Canagliflozin (Invokana) will need new warnings about the risks of developing ketoacidosis, urinary tract infections that require hospitalization and other serious illnesses related to taking the medications. Frequent Urination 2. Find out today if you are entitled to compensation for the pain and suffering you have endured. INVOKANA® is a class of type 2 diabetes drug known as an SGLT2 inhibitor. Three months prior to FDA approval of Invokana, concerns were raised by the agency regarding possible cardiovascular injury, kidney damage and bone health risk. Some UTIs have resulted in hospitalization. by Dr. Kiran Khanzada. If you are in the U.S. and have taken Invokana and experienced any one of these adverse effects, do not hesitate to contact a U.S. attorney at Carabin Shaw today. There are several known side effects of Invokana. Home » Blog » The Dangers of Combining Invokana with Crestor. Review the full Invokana information here, and speak to your health care provider if you have questions or concerns. Titusville, NJ. Invokana [package insert]. If your doctor fails to inform you about certain risks and you are harmed after following their recommendation, your legal rights may have been violated. According to clinical trials conducted by the FDA, canagliflozin increases users’ risk of leg and foot amputations, and that risk only increases for users who already underwent a previous amputation. The Dangers of Invokana Diabetic Medication Diabetes and Invokana. 79 cases against Invokana and Invokamet have recently been consolidated and appointed to the U.S. District Court of New Jersey. The makers of Invokana are also currently facing lawsuits from consumers who experienced unexpected side effects. Invokana reduces blood glucose via the kidneys, increasing glucose loss in the urine. In December 2015, the FDA warned that patients who are taking SGLT2 inhibitors should stop taking the drug and seek medical attention if they are …